Liverpool captain Virgil van Dijk is doubtful through injury, while this match comes too soon for Diogo Jota.
Joel Matip and Thiago Alcantara remain long-term absentees but Conor Bradley is back in contention.
Tottenham boss Ange Postecoglou says there was no "significant" injury news following Thursday's defeat at Chelsea but added that several players are are "feeling the effects of the game".
Timo Werner and Ben Davies are among six players who remain sidelined.
MATCH FACTS
Head-to-head
- Liverpool's only defeat in their past 29 home league games against Tottenham (W19, D9) was a 2-0 loss in May 2011.